标题：Prevalence of Septicaemia and Antibiogram of Different Etiological Agents in Patients of Intensive Care Units of a Tertiary Care Centre in Northern India
出版社：International Nepal Epidemiological Association (INEA)
摘要：Background Septicaemia is a leading cause of mortality in ICU patients. Any delay in diagnosis and /or antibiotic treatment have been shown to increase in mortality.We planned to study the prevalence, bacteriological profile of septicaemia along with their antibiogram in patients of different ICUs in a tertiary care Hospital, Northern region. Materials and Methods Blood culture was performed on total of 223 blood samples from 218 patients suspected for septicaemic episodes using Brain Heart Infusion (BHI) broth. The isolates were identified by standard microbiological techniques and their antibiotic susceptibility testing was performed by Kirby Bauer method. Results Bacterial growth was seen in 54 samples (54 episodes of septicaemia) from 49(22.47%) patients (40, 4, 5 from Neonatal ICU, Medicine ICU, Surgical ICU respectively). The commonest isolate was Staphylococcus aureus (45.45%) [80% in NICU, 12% in MICU & 8% in SICU], followed by Klebsiella (30.9%) [100% from NICU], and Pseudomonas aeruginosa (9.1%) [40% in NICU, 20% in MICU & 40% in SICU]. The Gram positive isolates showed high sensitivity against teicoplanin (96%), vancomycin (93%), netillin (76%), erythromycin (72%), & gentamicin (72%), The Gram negative isolates showed high sensitivity against imipenem & amikacin. Conclusion As prevalence of septicaemia and its etiology varies among hospitals, a rational protocol is warranted to manage sepsis of critically ill patients based on adequate knowledge of sensitivity pattern of prevalent causative agents. DOI: http://dx.doi.org/10.3126/nje.v3i4.9516
