摘要:Patient-specific blood flow modelling helps to predict surgical operation results, gives new noninvasive diagnostic methods, allows to investigate physiology of vascular pathologies. We develop numerical models for such medical applications. 1D blood flow model describes hemodynamics in the whole vascular network. 3D model of fluid flow can be embedded in the 1D model to zoom the domain of interest or to take into account pathologies or implants. We personalize the model, using patient-specific vascular structure and parameters. For some vascular regions extraction of patient-specific geometry can be automatic within developed technology. We verified the 1D model of blood flow. Two examples of real medical applications are presented. The method for FFR estimation is proposed. Also we used the 1D model for prediction of surgical occlusion treatment.