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  • 标题:Management of patients with metastatic colorectal cancer: economic consequences of different treatment programs
  • 本地全文:下载
  • 作者:Stefania Lopatriello ; Cristina Negrini ; Domenico Amoroso
  • 期刊名称:Farmeconomia. Health economics and therapeutic pathways
  • 印刷版ISSN:2240-256X
  • 出版年度:2009
  • 卷号:10
  • 期号:3
  • 页码:129-134
  • DOI:10.7175/fe.v10i3.173
  • 语种:Italian
  • 出版社:SEEd
  • 摘要:The clinical pattern of Metastatic ColoRectal Cancer patients, receiving first-line infusional 5-FU or oral capecitabine (CAP) chemotherapies, was valorized in the perspective of the Italian NHS. A cost-minimization analysis was implemented on the basis of retrospective data from 5 centers. 202 subjects: 126 receiving 5-FU-association, 10 5-FU-monotherapy; 31 CAP-association, 35 CAP-monotherapy. Therapeutic patterns differed as to chemotherapy administration resources consumption: 5-FU was administered in Day Hospital and CAP in the outpatient setting. Mean total cost/patient was in the range of € 6,841 (monotherapy-5-FU)- € 12,620 (association-5-FU) and € 2,056 (monotherapy-CAP)-€ 9,745 (association-CAP). The infusional administration route of 5-FU was the driver of costs.
  • 关键词:Oral;Infusional chemotherapy;Clinical pattern;Costs
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