期刊名称:Karbala International Journal of Modern Science
印刷版ISSN:2405-609X
电子版ISSN:2405-609X
出版年度:2017
卷号:3
期号:1
页码:39-45
DOI:10.1016/j.kijoms.2017.02.002
语种:English
出版社:Elsevier
摘要:Abstract In an extensive search program towards development of new hepatoprotective agents, a series of novel benzofluorenones have been synthesized. These newly synthesized benzofluorenone derivatives exhibited protection against carbon tetrachloride (CCl4)-induced hepatotoxicity. This activity was estimated by levels of biochemical parameters such as aspartate aminotransferase (AST), serum alanine transferase (ALT), serum alkaline phosphatase (SALP) and total proteins (TP) carried out by using regular assay kits. Graphical abstract Display Omitted