摘要:This study aimed to enhance students’ learning achievement of matter separation by using five science inquiry learning activities (12hours) on separation of natural substances. The participants, purposively selected, were 33 Grade 7 students in the first academic semester of 2011 at Ban-Nathung School in Sisaket province of Thailand. The data collecting tools consisted of a learning achievement test of matter separation and a survey of students’ attitudes towards learning science. The dependent sample t-test analysis indicated that the students obtained a post-achievement test score (mean 14.24, SD 2.45) higher than the pre-achievement test score (mean 7.73, SD 2.76) at the 0.05 level of statistical significance. However, the students obtained a retention test score (mean 14.09, SD 2.17) 30 days after the post-achievement test that was not different from the post- achievement test score at the 0.05 level of statistical significance. In addition, students’ attitudes towards learning science after the implementation of science inquiry learning activities (mean 89.00, SD 8.97) was statistically significantly higher than prior to using the activities (mean 77.76, SD 8.39) at the 0.05 level of statistical significance. In conclusion, the implementation of inquiry learning activities was effective to enhance students’ learning achievement of matter separation as well as their attitudes towards learning science.