摘要:Abstract: In this paper, we investigate the problem of conformation change in a network of coupled oscillator system with double well internal potential. Conformation change refers to the phenomena where all the oscillators in the network make a transition from one potential well to another potential well under the influence of external perturbation. We propose a novel approach based on information transfer in network dynamical systems to understand this phenomenon. We consider a heterogeneous network system where the internal dynamics of the oscillators are assumed to be nonidentical and the interconnecting Laplacian can also be asymmetric. The objective is to determine which of the network oscillator is most influential in driving the conformation dynamics. We show that the net information transfer of individual oscillators can be used to determine the most influential oscillator which can drive the entire network from one well to another well of the potential. We use three different network topologies to verify our proposed framework.