摘要：A finite element model (FEM) of human C0-C7 cervical spine has been developed as a baseline to study the biomechanical factors in spinal surgical intervention. To accurately simulate the anisotropic properties, the intervertebral disc was divided into nucleus, annulus matrix and annulus fiber, and it was simulated with viscoelastic and fabric material models. The nonlinear force-displacement curves of ligament experiments were implemented to simulate the elastic zone and neutral zone at low loads. The model was validated with experimental data on range of motion (ROM) for normal, non-degenerated cervical spines tested in flexion and extension, lateral bending, and axial rotation at loads of 0.33, 0.5, 1.0, 1.5, and 2.0 Nm, and intra-discal pressure (IDP) was validated against experiment data at loads of 2Nm and 5Nm. For lateral bending and axial rotation, the model was well within in vitro experimental standard deviation corridors for the whole load range. For extension and flexion, however, the error index of C3-C4, C4-C5, C5-C6 flexion were 0.268, 0.03, 0.124 and the C6-C7 extension was 0.046 respectively. The IDP result was in well agreement with the experiments. These results indicated the C0-C7 cervical spine model was biofidelic for static simulation of these motions.
