摘要:The goal of the study was the effectiveness in treatment addicted patients based on their personality profiles. 102 addicted patients from four different areas of Tehran included in this study. All patients were asked to complete IP IP-NEO and Substance Use Disorders scales before and after Methadone Maintenance Therapy (MMT) or detoxification. By means of opium test in six month period, according to their relapse & non-relapse. Findings revealed that there was significant difference between two groups in Neuroticism and patients without relapse had low level of Neuroticism than patients with relapse. We also compared personality profiles of patients with personality profiles of normal subjects. Normal subjects had high levels of Agreeableness and Conscientiousness, while addicted had higher neuroticism. The finding generally, evidenced the differences of personality of normal & addicted people.