摘要:Based on the reinforcement sensitivity theory (RST) normal and abnormal personality are located along a continuum. This study amid to compare the activity of brain/behavioral systems and mental health in addicts and normal individuals based on Jeffrey Gray theory. This research was a kind of cross sectional research. 50 addict and 50 normal subjects were chosen by convenience sampling method and based on age, sex, and educational level variables were matched. In this research of Gray-Wilson Personality Questionnaire (GWPQ) and depression, anxiety, Stress scales (DASS-21) were used. Data were analyzed by t- test in independent Groups. The results showed that there is a significant difference between normal and addict's individuals in both behavioral activation system (BAS)and behavioral inhibition system (BIS) (P <0/000), but there isn’t a significant difference in Fight/flight/freeze system (FFFS) and also there is a significant difference between mental health components in normal and addict's individuals (p <0/000). The results of this study conform to basic hypotheses of reinforcement sensitivity theory Gray and psychological conditions of addict's individuals.