摘要:Keyword: Keywords: SMSE, Advertising, Marketing, E-mail, Information Processing Abstrack:Abstract The source of economics matters in Indonesia is very depending of Small and Middle Scale Enterprise (SMSE). SMSE facing a big challenges which can be seen by how hard SMSE marketing their products. This condition effecting the selling volume become decreasing which make an impact that SMSE cannot increase their workers indeed some SMSE are releaseing their workers because they cannot pay the salary again. This condition make sure that we need to know the factor which influence the developing of SMSE so that SMSE can compete again. The use of information technology for advertising of SMSE products have an important role in operating SMSE because it can influence information processing for internet users. From the data which author have collected from quesionaire to know the influence of advertising progam and marketing by e-mail toward information processing, are analiyze by some tools which are validity and reliability test, normality test, P-plot test, correlation test, and non linear regression test. The result from this research show that advertising program of SMSE products in internet significanly influence the information processing and the marketing of SMSE product by e-mail significanly influence advertising information processing by internet users which can be seen from the equality: Ln Y %3D 2.491 + 0.032X1 + 0.014X2 + 0.008X3 + 0.002X4 +0.026X5 + 0.034X6 +0.018X7 + 0.003X8 + 0.005X9–0.010X10+0.054X11–0.018X12+0.005X13.