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  • 标题:Modelling the effect of screening on the spread of HIV infection in a population with variable inflow of infective immigrants
  • 本地全文:下载
  • 作者:Issa Shabani ; Estomih S. Massawe ; Oluwole Daniel Makinde
  • 期刊名称:Scientific Research and Essays
  • 印刷版ISSN:1992-2248
  • 出版年度:2011
  • 卷号:6
  • 期号:20
  • 页码:4397-4405
  • DOI:10.5897/SRE11.385
  • 语种:English
  • 出版社:Academic Journals
  • 摘要:This paper examines the combined effects of screening and variable inflow of infective immigrants on the spread of HIV/AIDS (human immunodeficiency virus/acquired immune deficiency syndrome) in a population of varying size. A nonlinear deterministic mathematical model for the problem is proposed and analysed qualitatively using the stability theory of differential equations. The results show that the reproductive number R0 >1 as the rate of inflow of infective immigrants increases leading to persistence of the disease in the population. However, the presence of screening greatly reduces the spread of HIV/AIDS.Numerical simulation of the model is implemented to investigate the sensitivity of certain key parameters on the spread of the disease.
  • 关键词:Human immunodeficiency virus/acquired immune deficiency syndrome; screening; infective immigrants; reproductive number; stability analysis; numerical simulation
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