摘要:Reiter’s syndrome is usually known as a clinical triad of arthritis, urethritis, and conjunctivitis. Peripheral nerve involvement in Reiter's syndrome is extremely rare. We report here on a 36-year-old man presenting to the orthopedic department with a chief complaint of lumbar and leg pain who initially was found to have lumbar intervertebral disc and was diagnosed as Reiter’s syndrome 3 months later. Human leukocyte antigen (HLA)–B27 test and bacterial culture of urine were positive. Clinical symptoms were relieved after conservative treatment with celecoxib, dexamethasone and antibiotics. This case suggests that Reiter's syndrome can present as lumbar spine lesions and should be considered in the differential diagnosis of lumbar intervertebral disc.