摘要:Adiponectin is a 244 – amino acid-long polypeptide, that acts as a hormone with anti-inflammatory and insulin sensitizing properties. serum adiponectin level correlates inversely with insulin resistance, and hypoadiponectinemia being is found in subjects with obesity or type 2 diabetes mellitus. The aim of the present study is to study the association of serum adiponectin level with the risk of type two diabetes mellitus. Sixty six diabetic patients and Twenty five controls were enrolled in this study. Adiponectin levels were significantly reduced in T2DM patients than in control group with mean and standard error of 8.98 ± 0.86μg/ml vs. 12.51 ± 1.53μg/ml, respectively. Adiponectin levels were significantly reduced in T2DM patients male with a mean and standard error of 5.58 ± 0.64 μg/ml more than that of female (10.95 ± 1.22 μg/ml).