期刊名称:Advances in Science and Technology Research Journal
印刷版ISSN:2080-4075
电子版ISSN:2299-8624
出版年度:2013
卷号:7
期号:19
页码:55-59
DOI:10.5604/20804075.1062364
语种:English
出版社:Society of Polish Mechanical Engineers and Technicians
摘要:Flow cytometry is a technology that simultaneously counts and then examines multiple physical and/or chemical characteristics of single particles, usually cells, as they flow in a fluid stream through a beam of light. The properties measured include a particle’s relative size, relative granularity or internal complexity, and relative fluorescence intensity. These characteristics are determined using an optical-to-electronic coupling system that records how the cell scatters incident laser light and emits fluorescence. One of the most significant applications is immunophenotyping of cells - the most important tool in diagnosis and monitoring haematological disorders, such as acute and chronic leukemia, lymphoma, monoclonal gammopathy, myelodisplastic and myeloproliferative diseases.