摘要：Pertussis is highly contagious. Neither natural infection nor vaccination provides lifelong immu- nity. As a consequence, epidemic peaks of pertus- sis occur every 3–4 years against a background of endemic transmission. There is little doubt that the use of pertussis vaccines has significantly impacted the global burden of this disease and prevented millions of deaths. However, pertussis continues to be a public health concern with growing evidence of a pertussis resurgence in a number of developed countries and deaths still occurring in vulnerable young infants, demonstrating the inadequacies of current pertussis control.
