摘要:The aim of this study was to verify the effect of an exercise protocol on the autonomic modulation of the heart rate of individuals with chronic obstructive pulmonary disease. Thirty-three of the initial 38 subjects with chronic obstructive pulmonary disease (COPD) completed the study. Heart rate variability (HRV) was evaluated using the POLAR® monitor. All subjects performed aerobic physical training and muscle strengthening. Rehabilitation occurred for 8 wks with 2 sessions•wk~(-1) lasting 50 min each. The variables in time domain (R-R interval, SDNN, RMSSD, and TINN), in frequency domain (LF, HF, and LF/HF), and nonlinear variables (SD1, SD2, Shannon Entropy, and Determinism) were analyzed. The findings indicate that in the frequency domain of variability, no variables were statistically significant. However, the RMSSD, SD1, and SD2 indices presented significant results after pulmonary rehabilitation, which positively influenced the autonomic modulation of the heart rate of COPD patients.