摘要:Nunes JED, De Agostini GG, Nicioli C, Ferreira FC, Baldissera V, Perez SEA. Resistance Training Program and Cytokines Before and After the Completion of a Fatigue Test. JEPonline 2010;13(3):40-48. Evidence suggests that exercise can induce the production of cytokines. We evaluated the effect of a 10-week circuit resistance training program (CRTP) on the acute effect of two fatigue tests (FT), the bench press (BP) and the leg press at 45˚ (LP), on the plasma concentrations of IL-6, IL-8, IL-10, IL-1β, and TNF . Volunteers took two FT, which were performed in three series with 50% of 1-RM done until exhaustion and 1- minute intervals between the series, before and after the CRTP. A total of 14 non-trained women, at 39.8±3.9 years, 60.6±6.6 kg and 163.6±6.6 cm, participated in the study. The plasma concentrations of IL-8 for the LP exercise, taken before and after the FT and from the pre- and posttraining periods, were (Pre: 4.4±2.6 and 5.7±1.0 pg/ml, p = 0,333) and (Post: 6.4±1.3 and 6.5±2.1 pg/ml, p = 0,797), respectively. For the BP exercise, the levels were (Pre: 3.7±3.9 and 9.0±2.6 pg/ml, p = 0,057) and (Post: 5.7±2.1 and 7.1±2.3 pg/ml, p = 0,164). IL-6, IL-10, IL-1β, and TNF did not reach the minimum limit of detection. Our data, then, support the idea that the two FT done do not provoke stress sufficient to alter the cytokinaemia.