摘要:Foss B, Sæterdal LR, Dyrstad SM. Weight Reduction in Obese Correlates with Low Morning Cortisol Increase. JEPonline 2014;17(3):70-76. The purpose of this study was to characterize how the stress system (i.e., the morning cortisol increase) is related to weight reduction by exercise in obesity. Twelve subjects with a body mass index >35 participated in a 22-wk exercise intervention program. The exercise program consisted of physical activity supplemented with diet and cognitive therapy seminars. Saliva was collected on two consecutive days after the intervention program. Eight of the 12 subjects decreased their body weight by 4.4% (P=0.023). Their average “morning” cortisol increase was 2.8 ng/ml (± 3.7). Seven of the subjects decreased their adipose tissue mass by 9.3% (P=0.032). A negative relationship was found between morning cortisol increase and body weight reduction (p = -0.76, P = 0.028). Thus, our study shows that weight reduction by exercise in obese subjects correlates with low morning cortisol increase. The higher the stress response experienced, the less reduction in body weight was found.