摘要：Heck TG, Petry MR, Maslinkiewicz A, Goettems-Fiorin PB, Ludwig MS, Saldiva PHN, Dal Ago P, Rhoden CR. Effects of Ambient Particles Inhalation on Lung Oxidative Stress Parameters in Exercising Rats. JEPonline 2014;17(3):58-69. This study examined the hypothesis that acute exercise exposed to urban ambient particles (UAP) inhalation could increase oxidative damage in the lung. Wistar rats were submitted to UAP during a 20 or 60 min swimming exercise. Longer periods of exercise (60 min exposure to UAP) showed higher lipid peroxidation (MDA and Chemiluminescence) in the lung and lower catalase activity. The findings indicate that the exposure of rats to urban ambient particles during 60 min of swimming exercise results in higher lipid peroxidation (MDA and Chemiluminesnce) and lower CAT activity in the lungs. Short-term exposure to particulate matter during exercise may be a biological risk, while longer periods of an exercise session with exposure to particles can exacerbate oxidative stress in the lungs.
