摘要:The aim of this study was to screen different solvent extracts of Cluasena excavata (leaves) to display potent antioxidant activity and also the total phenolic and flavonoid contents in order to find possible sources for future novel antioxidants in food and pharmaceutical formulations. Measurement of free radical scavenging activity (RSA) [reactions with 1,1-diphenyl- 2-picrylhydrazyl radical (DPPH), Nitric oxide scavenging assay by using UV-double beam spectrometer. Among the different extracts tested, the methanol extract showed significant antioxidant activity. Medicinal plants are widely spread in Tamil Nadu and their biological and phytochemical properties are not thoroughly evaluated. In this present study, crude extract of Cluasenaexcavation (leaves) were screened to regulate their active chemical constituents using conventional chemical tests (precipitation and color reagents) and antioxidant activities were determined using the DPPH radical scavenging method. The phytochemical tested shows the presence of various secondary metabolites such as alkaloids, flavonoids, glycosides, phenols, Terpenoids, saponins, and tannins etc. The plants revealed promising antioxidant activity, and require further studies to throw light on their chemical composition and antioxidant properties.