摘要:AbstractThe aim of this study was to determine the effectiveness of coping skills training based on “Marlatt Relapse Prevention Model” in relapse prevention and resiliency enhancement in people with substance dependency. In a semi-experimental study, 27 subjects with diagnosis of opiate use disorders in Jameiate Aftab Center of Tehran who had been successfully detoxified, were divided into two experimental group (13 subjects) and control group (14 subjects) that had been selected using available sampling method. The experimental group underwent 12 sessions of coping skills training and the control group did not receive any treatment. All subjects in the study were assessed by Conner-Davidson Resiliency Scale (CD-RIS) and morphine test before treatment, after treatment, and after a 4-month follow up stage. Data were analyzed using descriptive methods, χ2test, and ANCOVA. χ2test result showed that experimental and control groups (p<0/001) had a significant difference in relapse rates. In addition, ANCOVA showed a significant difference between two groups in resiliency enhancement at periods of post test and follow up (p<0/001). Study results indicated that coping skills training is effective in resiliency enhancement and relapse prevention in people with substance dependency.