摘要：ObjectiveNo doubt, obesity can cause for some metabolic syndromes, type 2 diabetes, hypertension, other cardiovascular disease and osteoarthritis. Given the undeniable role of sport in general health, the aim of this study was to assay the effect of regular exercise on serum level of Leptin in un-trained female.Materials and Methods:24 untrained-female subjects randomly divided in two groups (Control group and Experimental group). Blood samples were taken 48h before starting the aerobic training program. Then, experimental group performed the aerobic training program included running with 65-85% of individual maximum heart rate on treadmill for 3 session per week, 30minute per session and 8 consecutive weeks. Then another blood sample was taken following the training period. Serum levels of leptin of all subjects before and after the training period were measured using standard biochemical methods from all the subjects in both groups again.Results: Our results showed that the aerobic training resulted in a significant decrease in leptin serum in experimental group but no significant difference was seen in leptin serum in control group.Conclusion:The result showed that regular and light aerobic exercise could decrease leptin levels in un-trained female. So, decreases in serum leptin may be one mechanism by which weight loss improves physical function.
