摘要:AbstractMS is a disease of the central nervous system affecting all economic, financial, social, and emotional aspects of individual,family and community. The aim of the present study was to compare of personality characteristics and short -term memory of patient with Multiple sclerosis and healthy individuals. The statistical society is all of the patient with multiple sclerosis in Tabriz and from which 325 samples were selected using random sampling as e sample volume. In order for gathering data NEO-PI-IR and wechsler Memory scale(W.M.S) were utilized.The data were analyzed using Independent two-sample t-test. The results indicated that there is a significant different between personality characteristics and short -term memory of patient with multiple sclerosis and healthy individuals.