摘要:AbstractIn the cases of acute leukemia we may find beside the characteristic clinical syndromes, well described in the medical literature, also a series of psychological modifications. These last ones are reflected heterogeneously in the specialized literature. The purpose of this article was to investigate in the cases of patients with acute leukemia, the variations of depression and anxiety during three distinct phases of chemotherapy treatment (induction, consolidation and maintenance), for both genders. The estimated differences were tested with the help of the covariance analysis; the number of the blast cells in the peripheral blood was considered a factor of covariance for depression and anxiety. The results obtained proved significant increases of depression and anxiety in the phase of induction and consolidation, both depression and anxiety being in relation of covariance with the number of blast cells.