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  • 标题:Angiogenesis in Prevascularized Biomaterials: an in silico study
  • 本地全文:下载
  • 作者:Elif Seyma Bayrak ; Nan Xiao ; Sami I. Somo
  • 期刊名称:IFAC PapersOnLine
  • 印刷版ISSN:2405-8963
  • 出版年度:2015
  • 卷号:48
  • 期号:20
  • 页码:395-400
  • DOI:10.1016/j.ifacol.2015.10.172
  • 语种:English
  • 出版社:Elsevier
  • 摘要:AbstractAn agent-based model is developed to simulate angiogenesis in porous biomaterial scaffolds. This study investigates the influence of the existence of preperformed capillaries within the scaffolds on angiogenesis. Different configurations of capillary structures were tested and compared with empty scaffolds. Simulation results indicate that prevascularization of scaffolds before implantation supports rapid and stable blood vessel network development. The results were consistent with experimental studies from the literature.
  • 关键词:KeywordsAgent-based modelingangiogenesisprevascularized scaffolds
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