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  • 标题:Brain Genomics Superstruct Project initial data release with structural, functional, and behavioral measures
  • 本地全文:下载
  • 作者:Avram J. Holmes ; Marisa O. Hollinshead ; Timothy M. O’Keefe
  • 期刊名称:Scientific Data
  • 电子版ISSN:2052-4463
  • 出版年度:2015
  • 卷号:2
  • DOI:10.1038/sdata.2015.31
  • 语种:English
  • 出版社:Nature Publishing Group
  • 摘要:The goal of the Brain Genomics Superstruct Project (GSP) is to enable large-scale exploration of the links between brain function, behavior, and ultimately genetic variation. To provide the broader scientific community data to probe these associations, a repository of structural and functional magnetic resonance imaging (MRI) scans linked to genetic information was constructed from a sample of healthy individuals. The initial release, detailed in the present manuscript, encompasses quality screened cross-sectional data from 1,570 participants ages 18 to 35 years who were scanned with MRI and completed demographic and health questionnaires. Personality and cognitive measures were obtained on a subset of participants. Each dataset contains a T1-weighted structural MRI scan and either one (n=1,570) or two (n=1,139) resting state functional MRI scans. Test-retest reliability datasets are included from 69 participants scanned within six months of their initial visit. For the majority of participants self-report behavioral and cognitive measures are included (n=926 and n=892 respectively). Analyses of data quality, structure, function, personality, and cognition are presented to demonstrate the dataset’s utility.
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