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  • 标题:The Infant Gut Microbiome: Evidence for Obesity Risk and Dietary Intervention
  • 本地全文:下载
  • 作者:Petya T. Koleva
  • 期刊名称:Nutrients
  • 电子版ISSN:2072-6643
  • 出版年度:2015
  • 卷号:7
  • 期号:4
  • 页码:2237-2260
  • DOI:10.3390/nu7042237
  • 语种:English
  • 出版社:MDPI Publishing
  • 摘要:Increasing globally, particularly in children, obesity is a serious public health issue and risk factor for overweight and metabolic disease in later life. Both in experimental animal and human studies, advances in gene sequencing technologies have yielded intriguing possibilities for the role of the gut microbiome in later development of overweight status. Before translating study findings into practice, we must first reconcile inconsistencies between animal experimentation, and human adult and infant studies. Recent evidence for associations with gut microbiota and infant weight gain or child weight status, implicate Bacteroides and Lactobacillus species. Dietary manipulation with human milk and pre/probiotic formulations holds promise for preventing obesity.
  • 关键词:infant; nutrition; microbiome; human milk; prebiotics; probiotics; atopy; overweight infant ; nutrition ; microbiome ; human milk ; prebiotics ; probiotics ; atopy ; overweight
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