摘要:AbstractA novel engineering model reduction method is proposed in this paper that can be applied to a chemical reaction network (CRN) with chains of linear reactions. The reduced model is a delayed CRN with possibly different delays but with less state variables than the original model. As the first step of the model reduction, a decomposition method is also developed to transform chains with joint reactions into independent chains of linear reactions. The well known example of McKeithan's network is used as a case study to illustrate the basic concepts and the design method.