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  • 标题:Parameter and State Estimation of a Mathematical Model of Carbohydrate Intake ⁎
  • 本地全文:下载
  • 作者:A. Olay-Blanco ; A. Rodriguez-Liñan ; G. Quiroz
  • 期刊名称:IFAC PapersOnLine
  • 印刷版ISSN:2405-8963
  • 出版年度:2018
  • 卷号:51
  • 期号:13
  • 页码:73-78
  • DOI:10.1016/j.ifacol.2018.07.257
  • 语种:English
  • 出版社:Elsevier
  • 摘要:AbstractCarbohydrate intake is one of the main disturbances in blood glucose metabolism and one of the major care-issues in diabetes therapy. For this reason, the dynamics of glucose absorption after a meal intake must be included in glucose metabolism models. Current interest in developing patient-specific models has shown the necessity to estimate key parameters in models of carbohydrate intake, which cannot be measured with available sensor technology. In this contribution, we present a scheme to estimate a parameter and a state related to absorption of glucose in the intestine, which depend on the amount of carbohydrates ingested in a meal. The scheme is based on an adaptive observer with exponential convergence to estimate states and uncertain constant parameters.
  • 关键词:KeywordsParameter estimationpatient-specific modelsglucose metabolism modelingcarbohydrate intakeglucose dynamics
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