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  • 标题:Diabetic Gastroparesis Modeling and Observer Design
  • 本地全文:下载
  • 作者:Claudia Califano ; Emeric Scharbarg ; Nicolas Magdelaine
  • 期刊名称:IFAC PapersOnLine
  • 印刷版ISSN:2405-8963
  • 出版年度:2018
  • 卷号:51
  • 期号:13
  • 页码:97-102
  • DOI:10.1016/j.ifacol.2018.07.261
  • 语种:English
  • 出版社:Elsevier
  • 摘要:AbstractType 1 diabetes results from the lack of endogenous production of insulin by the pancreas. According to various references, 4% to 12% of diabetic patients are affected by gastroparesis which delays the digestion process. Gastroparesis is characterized by a constellation of gastrointestinal symptoms in association with delayed gastric emptying (GE). For the first time, a mathematical model is introduced to describe the glycemia dynamics for this significant class of patients. It is shown to yield to a nonlinear time delay model designed for estimation and control.
  • 关键词:KeywordsBiomedical systemsSystems biologytime-delay systemsobserver designglycemia dynamics
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