摘要:Bone is the connective tissue in the human body which consists of cells, fibers, and extracellular matrix. The bone matrix is the hardest part located in the outer layer of the bone, which is caused by the deposition of minerals in the matrix, so that the bone undergoes classification. The bone functions as a hard, rigid body frame, and provides a place or space for attachment of muscles and organs found in the human body. The simulation results using FEM showed that knee implants made with Ti6Al4V material had a total deformation of 0.15 mm, maximum principal stress of 17.012 MPa, and a maximum shear stress of 15.841 MPa. The analysis was performed using a variation of time 0 to 1.01 seconds.