摘要：AbstractThis work proposes an alternative framework for parametric bioimpedance estimation as a powerful tool to characterize biological media. We model the bioimpedance as an electrical network of parallelRC circuits,and transform the frequency-domain estimation problem into a time constant domain estimation problem by means of the distribution of relaxation times (DRT) method. The Fredholm integral equation of the first kind is employed to pose the problem in a regularized least squares (RLS) form. We validate the proposed methodology by numerical simulations for a synthetic biological electrical circuit, by using a multisine signal in the frequency range of 1kHz to 853kHz and considering an error in variables (EIV) problem. Results show that the proposed method outperforms the state-of-the-art techniques for spectral bioimpedance analysis. We also illustrates its potentiality in terms of accurate spectral measurements and precise data interpretation, for further usage in biological applications.
