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  • 标题:STUDY ON PREPARATION OF CINNAMALDEHYDE-HY- DROXYPROPYL-B-CYCLODEXTRIN: BASED ON RESPONSE SURFACE METHODOLOGY (RSM)
  • 本地全文:下载
  • 作者:Li Xiao ; Kun Qian ; Yu hua Guo
  • 期刊名称:Fresenius Environmental Bulletin
  • 印刷版ISSN:1018-4619
  • 出版年度:2018
  • 卷号:27
  • 期号:10
  • 页码:6610-6617
  • 语种:English
  • 出版社:PSP Publishing
  • 摘要:In this test, cinnamaldehyde-hydroxypropyl-ȕcyclodextrin inclusion complexes were prepared by aqueous solution stirring method. The RSM is used to optimize the process conditions. The inclusion ratio and the yield of inclusion complexes were used as response values to obtain cinnamaldehyde-hydroxypropyl-ȕ-cyclodextrin inclusions. The optimal conditions for inclusion of the compound were: ratio of molecules 1:1, inclusion time 3 h, and inclusion temperature 30°C. Cinnamaldehyde and hydroxypropyl-ȕ-cyclodextrin have formed inclusions, and the inclusion rate can reach 75% with a yield of 99.0%. Therefore, the inclusion process enables the preparation of a cinnamaldehyde inclusion compound, improves its solubility, and prepares the cinnamaldehyde from a volatile oil into a solid powder formulation.
  • 关键词:Cinnamaldehyde;hydroxypropyl-ȕ-cyclodextrin;inclusion rate;inclusion compound yield
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