摘要：Chronic kidney disease (CKD) is a disease that manifests itself with abnormalities in kidney structure or function. Inflammation and oxidative stress increase in kidney disease in parallel with the advancement of the disease. In addition, vitamin synthesis metabolism is also disrupted as a result of the decrease in kidney functions. Vitamins A and E are strong anti-inflammatories and antioxidants which protect the body against oxidative stress. Hence, the activation of these vitamins in CKD patients is of significant importance. The study was carried out with the participation of 139 people comprised of 79 volunteer patients diagnosed with Stage-5 CKD and 60 healthy volunteers (control). Demographic measurements of the participants were carried out and their biochemical parameters (glucose, urea, creatinin, AST, ALT, and LDL etc.) were determined via ELISA and spectrophotometric analyses. Serum A and E vitamin levels were determined via HPLC analysis.
