期刊名称:Beni-Suef University Journal of Basic and Applied Sciences
印刷版ISSN:2314-8535
电子版ISSN:2314-8543
出版年度:2015
卷号:4
期号:1
页码:52-59
DOI:10.1016/j.bjbas.2015.02.008
语种:English
出版社:Elsevier
摘要:AbstractNovel series of dialkylaminoalkyl-o-cresols incorporated with purine nucleus2a–b, benzothiazole nucleus5a–b,8a–band thiazole nucleus11a–d,13a–dwere synthesized through Mannich reaction. Structures of the newly synthesized compounds have been deduced on the basis of elemental analysis and spectral data. Antimicrobial activity evaluation was carried out for all synthesized compounds; most of them exerted comparable activity to ciprofloxacin and flucanazole. The thiazole derivatives11a,13c,13dare the most potent compounds.