摘要：THE PURPOSE OF THIS STUDY IS TO EVALUATE THE ASSOCIATION BETWEEN COELIAC DISEASE AND MENSTRUAL CYCLE ABNORMALITIES , FERTILITY DISORDERS OR PREGNANCY ASSOCIATED COMPLICATIONS. METHOD: THIS WAS A CASE CONTROL STUDY IN WHICH 32 FEMALE PATIENTS WITH COELIAC DISEASE AND 44 HEALTHY CONTROLS WERE COMPARED, THE MAIN CHARACTERISTICS EVALUATED IN BOTH GROUPS BEING: THE PRESENCE OF MENSTRUAL CYCLE ABNORMALITIES, FERTILITY DISORDERS OR COMPLICATIONS DURING PREGNANCY. RESULTS: THE ANALYSED GROUP WAS COMPOSED OF 32 WOMEN WITH COELIAC DISEASE AND 44 HEALTHY WOMEN. THE MEAN AGE WAS 31.78 YEARS VS 32.29 YEARS IN CONTROLS. THE FREQUENCY OF AMENORRHEA WAS HIGHER IN THE COELIAC DISEASE GROUP VS CONTROLS ( P=0.01). THE STRONGEST ASSOCIATIONS WERE OBTAINED BETWEEN COELIAC DISEASE AND COMPLICATIONS DURING PREGNANCY (P=0.00), MEAN AGE OF MENARCHE (13.65 YEARS VS 12,63 YEARS IN CONTROLS(P=0.00)), MEAN NUMBER OF PREGNANCIES (1.84 VS 2.39 ( P=0.005)) . CONCLUSIONS: THE OCCURRENCE OF A SIGNIFICANT CORRELATION BETWEEN CELIAC DISEASE AND REPRODUCTIVE DISORDERS (MEAN AGE OF MENARCHE, AMENORRHEA, NUMBER OF PREGNANCIES OR COMPLICATIONS DURING PREGNANCY) COULD SUGGEST TO CONSIDER CELIAC DISEASE DIAGNOSTIC PROCEDURES (SEROLOGICAL SCREENING) IN WOMEN AFFECTED BY THESE DISORDERS.
