摘要：INFLAMMATORY BOWEL DISEASES (IBD) CROHN’S DISEASE (CD) AND ULCERATIVE COLITIS (UC),ARE CHRONIC INFLAMMATORY DISORDERS OF UNKNOWN ETIOLOGY THAT APPEAR INGENETICALLY PREDISPOSED SUBJECTS, IN RESPONSE TO ENVIRONMENTAL FACTORS, MICROBIALAGENTS, INTESTINAL IMMUNE SYSTEM. ULCERATIVE COLITIS AND CROHN’S DISEASE AREASSOCIATED WITH A VARIETY OF EXTRAINTESTINAL MANIFESTATIONS, THEREBY THEY CAN BECONSIDERED SYSTEMIC DISEASES. THE MOST COMMON MANIFESTATIONS AFFECT THEMUSCULOSKELETAL AND DERMATOLOGIC SYSTEM. OTHER SITES ARE EYES,HEPATOPANCREATOBILIARY TRACT, KIDNEYS. ANEMIA IN IBD IS MULTIFACTORIAL IN ORIGIN,CHRONIC AND RECURRENT MANIFESTATION, THAT AFFECT PATIENT’S QUALITY OF LIFE. PATIENTSHAVE AN INCREASED RISK OF THROMBOEMBOLISM, REQUIRING THROMBOPROPHYLAXIS. WEPRESENT IN THIS LITERATURE REVIEW THE EXTRAINTESTINAL MANIFESTATIONS THAT ASSOCIATEWITH INFLAMMATORY BOWEL DISEASE.
