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  • 标题:Overlaps in the Pathogenesis of Rosacea and Atherosclerosis
  • 本地全文:下载
  • 作者:Aleksejs Zavorins ; Jūlija Voicehovska ; Jānis Ķīsis
  • 期刊名称:Proceedings of the Latvian Academy of Sciences, Section B. Natural, exact, and applied sciences, B dala. Dabaszinatnes
  • 印刷版ISSN:1407-009X
  • 电子版ISSN:1407-009X
  • 出版年度:2018
  • 卷号:72
  • 期号:3
  • 页码:152-159
  • DOI:10.2478/prolas-2018-0006
  • 语种:English
  • 出版社:The Academy
  • 摘要:Rosacea is a chronic inflammatory skin disease characterised by transient or persistent erythema, telangiectasia, papules, and pustules that predominantly involve central regions of the face. Recent studies have shown a possible clinical association between rosacea and cardiovascular diseases (CVDs). Rosacea and atherosclerosis are both known to have alterations in the innate immune system, enhanced oxidative and endoplasmic reticulum stress. The aim of this review is to delve deep into the pathogenesis of rosacea and atherosclerosis to uncover possible pathogenic overlaps between these chronic inflammatory diseases.
  • 关键词:rosacea; atherosclerosis; Toll-like receptor 2; LL-37; endoplasmic reticulum stress; oxidative stress
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