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  • 标题:Analytical methods for determination of bisphenol A, 4- tert-octylphenol and 4-nonylphenol in herrings and physiological fluids of the grey seal
  • 本地全文:下载
  • 作者:Marta Staniszewska ; Iga Nehring ; Lucyna Falkowska
  • 期刊名称:MethodsX
  • 印刷版ISSN:2215-0161
  • 电子版ISSN:2215-0161
  • 出版年度:2018
  • 卷号:5
  • 页码:1124-1128
  • DOI:10.1016/j.mex.2018.09.007
  • 语种:English
  • 出版社:Elsevier
  • 摘要:Graphical abstractDisplay OmittedHighlights•These methodologies have three key benefits.•Simultaneous determination of three endocrine disrupting phenol derivatives.•High sensitivity - detection by fluorescence detector.•Simply, short and not costly determination in blood and milk.Abstract•The aim of this work was to develop the methods of determination for phenol derivatives: bisphenol A (BPA), 4-tert-octylphenol (OP) and 4-nonylphenol (NP), in the whole body of herringClupea harengusand in physiological fluids of the Baltic grey sealHalichoerus grypus grypus(blood and milk).•Methods were based on liquid chromatography coupled with a fluorescence detector (HPLC-FL).•These methods were satisfactorily validated, each showing good recovery (>80%) and precision (RSD < 15%). Regarding the limit of quantification (LOQ), this was established at <2 ng g−1for herring, <0.07 ng cm-3for blood and <0.1 ng cm−3for milk.
  • 关键词:Phenol derivatives;Biological samples;Liquid chromatography;Fluorescence detector
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