期刊名称：Beni-Suef University Journal of Basic and Applied Sciences
印刷版ISSN：2314-8535
电子版ISSN：2314-8543
出版年度：2018
卷号：7
期号：4
页码：646-651
DOI：10.1016/j.bjbas.2018.07.009
语种：English
出版社：Elsevier
摘要：Graphical abstractWhere, 2a: 5-Iodo Salicylic acid & 2b: 3-bromo-5-hydroxy benzoic acidAr: 1-5Display OmittedAbstractA series of some novel azo derivatives of benzimidazole were prepared by coupling diazonium derivative of benzimidazole with various appropriate aromatic compounds. Confirmation of the chemical structure of the novel synthesized compounds 6a (1–5) & 6b (1–5) was substantiated by TLC, different spectral data IR,1H NMR, Mass spectra and elemental analysis. The synthesized compounds were evaluated for in-vitro antimicrobial and anti tubercular activities againstBacillus subtilis, Escherichia coli and Mycobacterium tuberculosis. The compounds exhibited weak, moderate, or high in-vitro antimicrobial and anti tubercular potency. Compounds6a2, 6a3, 6b2 and 6b3exhibited potential antimicrobial activity.
关键词：Azo derivatives;Benzimidazole;Antimicrobial and anti tubercular
