Objectives: Considering the importance and the role of scientific research in small and large scale programming, and also regarding the fact that researches should be in line with the major needs of the society, the aim of this study was to assess research needs in the field of behavioral science and prioritizing them from the viewpoint of mental health professionals in the city of Isfahan. Method: The current study was a cross sectional descriptive study which was carried out on 91 individuals consisting of psychiatrists, psychologists, health professionals, social workers and nurses in Isfahan. The research environment included Center for Research on Behavioral Science, physicians’ offices, and health and treatment centers in Isfahan. Data were gathered using Delphi method. Results: The different groups of subjects had the following viewpoints with regard to research priorities. psychiatrists: determining the position of the lost chain of social work in the field of psychiatry and comparing it with universal models, as well as the assessment of familial, occupational, educational and other factors in psychiatric patients psychologists: the evaluation of sexual needs as well as approaches to its control and equilibrium regarding religious culture, and assessing parents’ relationship with each other and with their children on the addiction of adolescents social workers: the effectiveness of pre-marriage social trainings on marriage compatibility, and the efficiency of social interventions in divorce prevention occupational therapists: the psychopathology of families with at least one patient with psychiatric illness, and the role and importance of sensual homogeneity in the treatment of various mood disorders mental health professionals: addiction in physicians, health personnel, employees and workers nurses: family training and its effect on the behavior of psychiatric patients, as well as causes and factors related to relapse in psychiatric disorders. Conclusion: According the present need assessment from professionals involved in mental health and behavioral science, research in the fields of addiction, suicide and family has higher priority.