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  • 标题:Adaptive stimulation strategy for selective brain oscillations disruption in a neuronal population model with delays
  • 本地全文:下载
  • 作者:Jakub Orlowski ; Antoine Chaillet ; Mario Sigalotti
  • 期刊名称:IFAC PapersOnLine
  • 印刷版ISSN:2405-8963
  • 出版年度:2019
  • 卷号:51
  • 期号:34
  • 页码:250-251
  • DOI:10.1016/j.ifacol.2019.01.044
  • 语种:English
  • 出版社:Elsevier
  • 摘要:ganglia. Synchronous beta (13–30 Hz) oscillations between the population of excitatory neurons in the subthalamic nucleus (STN) and inhibitory neurons in the external globus pallidus (GPe) are correlated with increased bradykinesia (slowness of movement) as well as rigidity [Hammond et al. 2007; Little et al. 2012]. Deep brain stimulation (DBS) is a symptomatic treatment of PD symptoms, consisting in delivering high-frequency electrical stimulation through permanently implanted electrodes [Benabid et al. 1991]. While we cannot yet with certainty describe neither the exact role of beta oscillations in PD nor the precise way DBS influences the neuronal.
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