摘要：This research was conducted to describe the therapeutic effect of ivermectin and piperazine citrate on blood profile in commercial layer birds and rural poultry. Two experiments named 1 and 2 were performed representing commercial layer birds and rural poultry respectively. Each experiment was consisted of 4 groups of 15 birds each named A, B, C, D, (Experiment No 1) and W, X, Y and Z (Experiment No 2). To make the birds parasitic free, Albendazole @14mg /Kg were administered in all birds. In subgroups A, B, C, W, X and Y Ascaridia galli infection was inoculated orally @ dose rate of 2500 embryonated eggs per bird using crop tube. To confirm infestation 5 birds were euthanized from each treatment group at day 28th of post infection. Ivermectin @ dose rate of 200µg/kg was given in birds of treatment groups A and W, and Piperazine citrate @ dose rate of 32 mg/100 kg in birds of treatment groups C and Z. At day 10th (post treatment) six birds from each group were blood sampled to check blood profile. Blood analysis showed same (P > 0.05) effect of both anthelmintics on serum cholesterol, serum T3, serum creatinine, serum cortisol level, ESR and respiratory rate of infested birds whilst Piperazine citrate administration showed higher (P < 0.05) serum T4 level, and lower (P < 0.05) serum urea level in infested birds.
