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  • 标题:A New Dolabrane Dinorditerpene from Ceriops tagal
  • 本地全文:下载
  • 作者:Xin Wu ; Hongbo Liao ; Hongyu Lu
  • 期刊名称:Open Access Library Journal
  • 印刷版ISSN:2333-9705
  • 电子版ISSN:2333-9721
  • 出版年度:2016
  • 卷号:3
  • 期号:8
  • 页码:1-6
  • DOI:10.4236/oalib.1102957
  • 语种:English
  • 出版社:Scientific Research Pub
  • 摘要:A new dolabrane dinorditerpene, tagalsine X(1), was isolated from the leaves of Ceriops tagal, along with five known analogues (2-6). Their structures were established on the basis of spectroscopic data or comparison with the literatural data. Their cytotoxic activities against four human carcinoma cell lines (CNE-2, HCT-116, HepG2and A549) were also evaluated, which displayed that only compound 2 had significant cytotoxicity against those cell lines with IC50 values of 13.57, 42.32, 11.21 and 15.23 μM, respectively.
  • 关键词:Ceriops tagalDolabraneTagalsine XCytotoxicity
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