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  • 标题:Complete genome sequencing of Comamonas kerstersii 8943, a causative agent for peritonitis
  • 本地全文:下载
  • 作者:Xiawei Jiang ; Wenhong Liu ; Beiwen Zheng
  • 期刊名称:Scientific Data
  • 电子版ISSN:2052-4463
  • 出版年度:2018
  • 卷号:5
  • DOI:10.1038/sdata.2018.222
  • 语种:English
  • 出版社:Nature Publishing Group
  • 摘要:Because of poor differentiation among the members of genus Comamonas using phenotypic methods, human infections caused by C. kerstersii are sporadically reported in the literature. Here, we represent the first complete genome sequence of C. kerstersii 8943, which caused peritonitis in a patient with continuous ambulatory peritoneal dialysis (CAPD). The complete genome with no gaps was obtained using third-generation Pacific Biosciences (PacBio) RSII sequencing system with single-molecule real-time (SMRT) analysis. Protein-coding genes, rRNAs and tRNAs were predicted. Functional annotations of the genome using different databases revealed several genes related to pathogenicity including antibiotic resistance genes and prophages. Our work demonstrates that whole genome sequencing can enhance the resolution of clinical investigations and our data can be used as a reference genome during the rapid diagnosis of C. kerstersii infections in the future.
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