摘要：This study was conducted to determine alteration of milkfish (Chanos chanos) organs (gills, liver andkidney) cultured in cadmium (Cd) and lead (Pb) contaminated ponds. The method used in this researchwas descriptive. Samples for research were obtained from Patuguran, Rejoso District, Pasuruan. Themain parameters were the damage of the gills, liver and kidney of milkfish. Data were analyzed byanalysis of variance (ANOVA), continued with least significant difference (LSD) and regressionanalysis. The result indicated that the heavy metals were present in water and sediment. Theirconcentrations were Pb 0.49 ppm and Cd 0.50 ppm, for water and sediment, respectively. Theobservation on organ histopathology revealed that gills experienced fusion, hyperplasia and necrosis.The liver showed cells degeneration, congestion and necrosis. Kidney experienced atrophy, cloudyswelling and glomerular hyalinization. The degree of organ damage was affected by length of rearingtime. This research indicated that cadmium and lead polluted the fishpond in Rejoso District, Pasuruanand affected the organs of milkfish.
