摘要：Lead is a naturally-occurring element that can be harmful to humans when ingested or inhaled. Thedetermination of lead in blood serum and urine is a very important clinical investigation procedure. The aimof this investigation was to determine the concentration of lead (Pb) in blood serum and urine samples ofsilver jewellery workers (SJW), because of their exposure to lead fumes and lead oxide dust during theirroutine activities of silver jewellery processing affecting many systems in their body. The relationship betweenserum lead levels and urinary lead levels with health effects were also assessed in a cross sectional study ofthe SJW group of Ajmer city. Blood and urine samples were collected from 40 SJW. Lead concentration inthe samples was determined by atomic absorption spectrophotometer (AAS). The results indicate that thelevel of serum lead concentrations ranging from 0.4 to 142.65 µg/dl and the urinary lead level concentrationsranging from 0.66 to 134.98 µg /dl. The prominent findings among the lead exposed SJW group wereimpaired concentration, encephalopathy, fatigue, abdominal colic, spontaneous abortion, abnormal sperm,anaemia, kidney failure, etc. Such results might point that lead exposure increases the serum and urinarylead levels of SJW group. Lead poisoning affects multiple organ systems and can cause permanent damage.
