摘要：Soil samples were collected from different agro-climatic regions of north Telangana region of Andhra Pradesh.Sterilized nitrogen free BG-11 medium was used for isolation of nitrogen fixing cyanobacteria. Antifungalactivity of four strains of Tolypothrix were studied. Methanolic extracts from biomass of selected Cyanobacteriawere isolated and screened against four strains of fungi (Candida albicans, Candida guilliermondii, Aspergillusniger and Aspergillus fumigatus). The growth of all fungal strains tested were inhibited by the culture extractsand C-phycocyanin. Bioassay studies of Eri silkworm expressed no symptom of ill-health after feeding theC-phycocyanin treated castor leaves (Ricinus cummunis), and body weight and silk gland weights were alsoincreased compared to control sample. The present study is also envisaged on the impact of phycocyanin ofTolypothrix species on the carbohydrate content and amylase activity in Eri silkworm (Samia cynthia ricini).According to the obtained results it is concluded that extracts from Tolypothrix sp. could be used traditionallyin the treatment of microbial infections and also for the increase of carbohydrate and amylase activity in thesilkworm under investigation.
