摘要:Three-dimensional (3D) models are a useful tool for cranial deformation analysis in infants. The registration of the head 3D models to a known coordinate system is vital for the obtainment of parameters and indexes that quantify deformation. In this study, three registration methodologies have been tested based on the principal component analysis (PCA) without tie points, and PCA measuring manually two and three identified tie points. Results show that the approach using PCA plus three manually identified tie points provides enough accuracy for the given application.