摘要：Nature provides vast sources of potent biological compounds that can help the humanity in their routine life, i.e. health, agriculture, etc. Plants are one of the main natural sources that can secrete or incorporate bioactive compounds with efficacy against pathogenic microorganisms. That is the reason that we have explored the antibacterial activity of methanol, n-hexane, ethyl acetate and chloroform extracts of plant species Datura alba. The extract from leaves, stem, roots and seeds were tested in vitro against four bacterial strains by agar diffusion methods. The results suggested that leaf extracts have the highest inhibitory potential againstK. pneumoniae and E. coli. The extracts from other parts showed moderate to low activities against the tested bacterial strains. The study reveals that the leaves of D. albahas the highest concentration of secondary metabolites and may prove to be an important candidate in pharmaceutical formulations against these two pathogens.
